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. 2016 Jun 28;10:2095–2107. doi: 10.2147/DDDT.S109287

Table 1.

Effect of sitagliptin on BW, HW, and blood glucose in control and diabetic rats

BW (g)
HW/BW ratio Blood glucose (mg/dL)
Baseline 90 days Baseline 90 days
Control 166.92±4.49 269.60±6.58 0.39±0.02 95.40±4.85 93.66±4.47
Sitagliptin 150.33±5.89 296.51±9.71 0.40±0.16 99.74±3.71 93.49±4.75
Diabetic 161.20±3.77 142.10±6.62*** 1.01±0.22** 307.00±11.45*** 444.12±14.35***
Diabetic + sitagliptin 170.83±3.91 214.67±8.61# 0.48±0.06## 322.50±16.71 177.83±10.55###
F probability >0.05 <0.001 <0.05 <0.001 <0.001

Notes: Data are mean ± SEM (N=8).

**

P<0.01 and

***

P<0.001 for control and

#

P<0.05,

##

P<0.01, and

###

P<0.001 for diabetic.

Abbreviations: BW, body weight; HW, heart weight; SEM, standard error of the mean.