Table 3: Main results (time horizon = 5 yr).
| Strategy | Average total costs ($CAD) | Incremental cost ($CAD) | QALY | QALYs gained | ICER* ($CAD) |
|---|---|---|---|---|---|
| Base case | |||||
| IVT | 124 419 | - | 1.273 | - | - |
| MT + IVT | 126 939 | 2 520 | 1.484 | 0.210 | 11 990 |
| Efficacy based on ESCAPE trial14 | |||||
| IVT | 122 901 | - | 1.265 | - | - |
| MT + IVT | 132 224 | 9 323 | 1.613 | 0.348 | 26 815 |
| Severe stroke | |||||
| IVT | 116 826 | - | 0.933 | - | - |
| MT + IVT | 125 517 | 8 691 | 1.039 | 0.106 | 81 651 |
Note: Numbers may appear inexact because of rounding. $CAD = Canadian dollars in 2015, ICER = incremental cost-effectiveness ratio, IVT = intravenous thrombolysis, MT = mechanical thrombectomy, QALY = quality-adjusted life-year.
*Incremental cost per QALY gained.