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. 2016 Apr 6;4(2):E132–E140. doi: 10.9778/cmajo.20150036

Table 2: Motivation for research efforts reported by authors aware of existing RCT evidence.

RCT-related motivation No. (%) studies
Studies with only 1 
RCT-related motivation
n = 125
All studies*
n = 213
Assess effects in the "real world" 41 (32.8) 80 (37.6)
Assess different outcomes 34 (27.2) 68 (31.9)
RCT evidence inconclusive or inconsistent 23 (18.4) 55 (25.8)
   Compared with randomized evidence 6 (4.8) 15 (7.0)
   Compared with randomized and nonrandomized evidence 17 (13.6) 40 (18.8)
Study specific patient population 20 (16.0) 50 (23.5)
Other 7 (5.6) 21 (9.9)
None - 19 (8.9)

Note: RCT = randomized control trial.

*For study details, see Appendix 4 (available at www.cmajopen.ca/content/4/2/E132/suppl/DC1).