. 2016 Jun 10;59(1):16–24. doi: 10.3164/jcbn.15-122

Table 1.

Production of 8-oxo-dG from dG by H₂O₂ or LOOH with or without Fe²⁺

Substrate*	Fe²⁺ (µmol/L)	Oxidant (50 µmol/L)
Substrate*	Fe²⁺ (µmol/L)	Vehicle	H₂O₂	LOOH
		Produced number of 8-oxo-dG per 10⁵ dG**
dG (250 µmol/L)	0	0.67 ± 0.30^a	1.91 ± 0.39^a	3.35 ± 0.65^b
	0.5	1.27 ± 0.06^a	1.89 ± 0.20^a	3.59 ± 0.47^b
	10	5.04 ± 0.29^c	11.55 ± 0.82^d	8.73 ± 1.86^e

*dG was incubated with oxidants as shown in Materials and Methods. The commercial dG originally contained 8-oxo-dG at levels of 0.58 ± 0.08 number per 10⁵ dG, and the present results include the original amounts of 8-oxo-dG. **Values are mean ± SD (n = 6) and different superscript letters indicate statistically significant differences (p<0.05).