. 2016 Jun 10;59(1):16–24. doi: 10.3164/jcbn.15-122

Table 5.

Production of 8-oxo-dG by H₂O₂ or LOOH in HepG2 cells

Pretreatment with	Oxidant (100 µmol/L)
Pretreatment with	Vehicle	H₂O₂	LOOH
	Produced number of 8-oxo-dG per 10⁵ dG¹
None	0.08 ± 0.04^a	0.38 ± 0.15^b	0.23 ± 0.12^a,b,c,d
Mercaptosuccinate²	0.11 ± 0.03^a,c	0.34 ± 0.11^b,d	0.61 ± 0.04^e

¹Values are mean ± SD (n = 6) and different letters indicate statistically significant differences (p<0.05) in the same line. ²HepG2 cells were pre-incubated with 500 µmol/L mercaptosuccinate and then were exposed to H₂O₂ or LOOH.