Table 1.

Effect of traxoprodil on locomotor activity in mice

Treatment (mg/kg)	Distance traveled (cm)
saline (control group)	1014 ± 151.8
traxoprodil 5	915.0 ± 92.10
traxoprodil 10	738.5 ± 49.93
traxoprodil 20	912.0 ± 75.87
traxoprodil 40	789.1 ± 119.8
imipramine 30	653.9 ± 99.38

Traxoprodil, imipramine and saline were administered i.p. 60 min before the test. Distance traveled was recorded between the 2nd and the 6th min of the test. The data are presented as the means ± SEM. Each experimental group consisted of 8 animals. The results were considered statistically significant if p < 0.05 (one-way ANOVA followed by Dunnett’s post hoc test)