Table 2.
Multiple regression on baseline cognitive functioning predicting post-operative IL-6 (N = 135)
| Model | B | SE | ß | 95 % CI | P value |
|---|---|---|---|---|---|
| Step 1 | |||||
| Education | 2.056 | 6.725 | 0.028 | −11.256–15.369 | 0.760 |
| Household income | −2.876 | 2.115 | −0.124 | −7.063–1.310 | 0.176 |
| Smoking status | −3.426 | 9.959 | −0.031 | −23.140–16.287 | 0.731 |
| BMI | 0.677 | 0.653 | 0.093 | −0.616–1.970 | 0.302 |
| Baseline depression symptoms (BDI) | 0.003 | 0.417 | 0.001 | −0.823–0.829 | 0.994 |
| Cardiopulmonary bypass | 1.764 | 6.764 | 0.024 | −11.625–15.154 | 0.795 |
| Number of grafts | −0.659 | 2.539 | −0.023 | −5.685–4.367 | 0.796 |
| Chronic illness burden | −6.894 | 6.077 | −0.141 | −18.923–5.135 | 0.259 |
| Diabetes | −2.414 | 8.973 | −0.033 | −20.176–15.348 | 0.788 |
| EuroSCORE | −0.129 | 1.060 | −0.012 | −2.227–1.969 | 0.903 |
| Baseline IL-6 | 4.841 | 1.672 | 0.265 | 1.531–8.150 | 0.004 |
| Step 2 | |||||
| Education | 3.131 | 6.622 | 0.042 | −9.978–16.239 | 0.637 |
| Household income | −1.467 | 2.163 | −0.063 | −5.748–2.814 | 0.499 |
| Smoking status | −5.360 | 9.817 | −0.049 | −24.793–14.073 | 0.586 |
| BMI | 0.443 | 0.649 | 0.061 | −0.843–1.728 | 0.497 |
| Baseline depression symptoms (BDI) | −0.040 | 0.410 | −0.009 | −0.853–0.772 | 0.922 |
| Cardiopulmonary bypass | 2.061 | 6.645 | 0.028 | −11.093–15.216 | 0.757 |
| Number of grafts | −1.338 | 2.511 | −0.048 | −6.309–3.632 | 0.595 |
| Chronic illness burden | −6.478 | 5.972 | −0.133 | −18.299–5.344 | 0.280 |
| Diabetes | −2.212 | 8.814 | −0.030 | −19.660–15.237 | 0.802 |
| EuroSCORE | −0.249 | 1.042 | −0.022 | −2.313–1.814 | 0.811 |
| Baseline IL-6 | 4.974 | 1.643 | 0.273 | 1.721–8.227 | 0.003 |
| Baseline MoCA score | −13.456 | 5.739 | −0.212 | −24.818–−2.094 | 0.021 |
NB step 1 R 2 = 0.107, step 2 R 2 = 0.145, ∆R 2 = 0.039, p = 0.021