Table 1. Pharmacokinetic parameters obtained from literatures.
ER | SU | ||
---|---|---|---|
CLER/F (mL·kg−1·d−1) | 19 000 | CLSU/F (mL·kg−1·d−1) | 254 000 |
Vc, ER/F (mL/kg) | 885 | Vc, SU/F (mL/kg) | 323 00 |
QER/F (mL·kg−1·d−1) | 763 | QSU/F (mL·kg−1·d−1) | 708 000 |
Vp, ER/F (mL/kg) | 168 | Vp, SU/F (mL/kg) | 284 00 |
ka, ER (d−1) | 22.6 | ka, SU (d−1) | 50.9 |
– | – | Fm, SU | 0.583 |
– | – | Vm, SU/F (mL/kg) | 1 710 |
– | – | CLm, SU/F (mL·kg−1·d−1) | 247 000 |