Figure 1.

A,B) DKK3 expression in NOM, which was localized in the cell membrane of suprabasal cell layers, however absence of staining was detected in the basal layer; scale bars: A) 100 μm; B) 50 μm. C,D) OLK Mild dysplasia, DKK3 staining was localized in the cytoplasm of the basal layer and in the cell membranes of suprabasal layer; scale bars: C) 200 μm; D) 100 μm. E,F) OLK severe dysplasia, the staining was localized in the cytoplasm as in mild dysplasia; however, the percentage of cytoplasmic positive cells were higher in severe dysplasia compared with mild dysplasia; scale bars: E) 200 μm; F) 100 μm.