Table 1. Comparison of clinicopathologic characteristics between LN-negative SRC and non-SRC GC patients.
Variable | SRC | Non-SRC | P | ||
---|---|---|---|---|---|
No. ofPatients(n = 90) | % | No. ofPatients(n = 390) | % | ||
Age, years | |||||
Mean | 57.1 | 57.7 | 0.646 | ||
SD | 10.6 | 11.7 | |||
Sex | |||||
Male | 64 | 71.1 | 285 | 73.1 | 0.696 |
Female | 26 | 28.9 | 105 | 26.9 | |
Tumour location | |||||
Upper stomach | 20 | 22.2 | 131 | 33.6 | 0.141 |
Middle stomach | 28 | 31.1 | 103 | 26.4 | |
Lower stomach | 28 | 31.1 | 116 | 29.7 | |
Overlapping | 14 | 15.6 | 40 | 10.3 | |
AJCC stage | |||||
1 | 48 | 53.3 | 275 | 70.5 | 0.006 |
2 | 29 | 32.2 | 85 | 21.8 | |
3 | 13 | 14.5 | 30 | 7.7 | |
Tumour grade | |||||
1 | 12 | 13.3 | 74 | 19.0 | 0.161 |
2 | 19 | 21.1 | 103 | 26.4 | |
3 | 59 | 65.6 | 213 | 54.6 | |
Tumour stage | |||||
T1a | 16 | 17.8 | 185 | 47.4 | <0.001 |
T1b | 5 | 5.6 | 26 | 6.7 | |
T2 | 27 | 30.0 | 64 | 16.4 | |
T3 | 29 | 32.2 | 85 | 21.8 | |
T4 | 13 | 14.4 | 30 | 7.7 | |
Perineural invasion | |||||
Negative | 42 | 46.7 | 226 | 57.9 | 0.060 |
Positive | 48 | 53.3 | 164 | 42.1 | |
Vascular invasion | |||||
Negative | 77 | 85.6 | 348 | 89.2 | 0.358 |
Positive | 13 | 14.4 | 42 | 10.8 | |
Number of retrieved LNs | |||||
<15 | 9 | 10.0 | 21 | 5.4 | 0.143 |
≥15 | 81 | 90.0 | 369 | 94.6 | |
Chemotherapy | |||||
Yes | 29 | 32.2 | 106 | 27.2 | 0.363 |
No | 61 | 67.8 | 284 | 72.8 |
Abbreviations: SRC, Signet Ring Cell. SD, Standard Deviation. AJCC, American Joint Committee on Cancer, 7th Edition. LNs, Lymph Nodes.