Table 3. Univariate analyses of prognostic factors for relapse-free survival.
| Characteristic | Hazard Ratio | 95% CI | P |
|---|---|---|---|
| SRC histology | 1.83 | 1.23 to 2.70 | 0.003 |
| Age at diagnosis | 1.03 | 1.01 to 1.04 | <0.001 |
| Female sex | 1.21 | 0.83 to 1.78 | 0.323 |
| AJCC stage | |||
| 1 | 1.00 | <0.001 | |
| 2 | 4.10 | 2.78 to 6.03 | |
| 3 | 9.77 | 8.23 to 12.04 | |
| Tumour grade | |||
| 1 | 1.00 | 0.002 | |
| 2 | 1.18 | 0.82 to 1.71 | |
| 3 | 2.89 | 1.60 to 5.20 | |
| Tumour stage | |||
| T1a | 1.00 | <0.001 | |
| T1b | 1.74 | 0.99 to 3.07 | |
| T2 | 3.33 | 2.22 to 4.98 | |
| T3 | 3.51 | 1.58 to 7.82 | |
| T4 | 5.81 | 3.84 to 8.78 | |
| Tumour location | |||
| Upper stomach | 1.00 | 0.294 | |
| Middle stomach | 0.56 | 0.28 to 1.27 | |
| Lower stomach | 1.32 | 0.88 to 1.99 | |
| Overlapping | 1.05 | 0.71 to 1.56 | |
| Perineural invasion | 1.85 | 1.32 to 2.60 | <0.001 |
| Vascular invasion | 2.84 | 1.91 to 4.22 | <0.001 |
| Number of retrieved LNs | 2.23 | 0.98 to 5.07 | 0.055 |
| Chemotherapy | 2.49 | 1.78 to 3.48 | <0.001 |
Abbreviations: SRC, Signet Ring Cell. AJCC, American Joint Committee on Cancer, 7th Edition. LNs, Lymph Nodes.