Table 5.
Incremental costs compared with current pathway (in screening population of 698 500 pregnant women) for range of uptake values for non-invasive prenatal testing (NIPT) and invasive prenatal diagnosis (IPD) in high risk pregnancies, using national data
| Scenario | Uptake (%) | Incremental costs* (£000) | ||||
|---|---|---|---|---|---|---|
| NIPT | IPD | Total | 1/150 | 1/150—no direct IPD | ||
| Main analysis | 72.5 | 20.0 | 91.0 | −46 | −643 | |
| Lowest NIPT uptake (Whittington Hospital NHS Trust) | 68.5 | 25.9 | 94.4 | 235 | −527 | |
| Highest NIPT uptake and highest total uptake (Salisbury NHS Foundation Trust) | 96.6 | 3.4 | 100.0 | −427 | −337 | |
| Lowest total uptake (Barking, Havering and Redbridge University Hospitals NHS Trust) | 74.5 | 13.9 | 88.5 | −404 | −728 | |
Uptake figures were derived from table 1 but include trisomy 21 only.
*At NIPT test costs £250.