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. 2016 Jul 6;6:29105. doi: 10.1038/srep29105

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Copyright © 2016, Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Jejunal explants from 4 different animals were exposed for 4 hours, to diluent or 10 μM toxins and gene expression was analyzed with a 60 K microarray. (Panel A): Venn diagram illustrating the overlaps between the probes significantly up- or down-regulated in response to DON, deepoxy-DON (DOM-1) and 3-epi-DON treatment. (Panel B): Principal Component Analysis of differentially expressed probes between DON, deepoxy-DON (DOM-1), 3-epi-DON and control (747 with BH adjusted p-value < 0.05). (Panel C): Heat map representing differentially expressed probes between DON, deepoxy-DON (DOM-1), 3-epi-DON and control explant. Red and green colors indicate values above and below the mean (average Z-score) respectively. Black color indicates values close to the mean.