. Author manuscript; available in PMC: 2017 May 1.

Published in final edited form as: Clin Chim Acta. 2016 Mar 3;456:128–136. doi: 10.1016/j.cca.2016.02.022

Table 4.

Clinical sensitivities of HM-ELISA and HM-ELISA+PSAM for plasma samples in various ranges of HIV concentrations.

Range No.	RNA viral load (copies/ml)	Method	Total No. positives	No. Positives by test	Clinical sensitivity, %	Lower - Upper confidence interval
1	≤ 3,000	HM-ELISA	14	0	0	0 – 0
1	≤ 3,000	HM-ELISA+PSAM	19	10	52.63	30.2 – 75.1

2	3,000 – 30,000	HM-ELISA	46	15	32.61	19.1 – 46.2
2	3,000 – 30,000	HM-ELISA+PSAM	46	42	91.30	83.2 – 99.4

3	≥ 30,000	HM-ELISA	42	22	52.3	37.2 – 67.4
3	≥ 30,000	HM-ELISA+PSAM	41	41	100	100 – 100

1 & 2	≤ 30,000	HM-ELISA	60	15	25.0	14.0–35.96
1 & 2	≤ 30,000	HM-ELISA+PSAM	65	52	80.0	70.3–89.7

2 & 3	≥ 3,000	HM-ELISA	88	37	42.04	31.7 – 52.4
2 & 3	≥ 3,000	HM-ELISA+PSAM	87	83	95.40	91.0 – 99.8

1, 2&3	All positive	HM-ELISA	102	37	36.27	26.9 – 45.6
1, 2&3	All positive	HM-ELISA+PSAM	106	93	87.74	81.5 – 94.0