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The effects of TPPP3 on cell apoptosis and cell cycle. (A) Cell death was assessed by Annexin V staining and flow cytometry. (B) Cell cycle analysis was performed by flow cytometry after knockdown of TPPP3 in A549 and H1299 cells. (C) Western blot showed the expression of AKT, p-AKT, p-STAT3, STAT3, Survivin, CyclinD1, and BCL-2 in A549 and H1299 cells after TPPP3 silencing. Data were quantified via densitometric analyses from at least three independent experiments. **P<0.01.
