Table 2.

Functional categories of proteins differentially expressed in sit4Δ cells. Proteins differentially expressed (sit4Δ vs parental cells) were sorted into functional categories according to MIPS (Munich information center for protein sequences). Proteins belonging to each category are indicated, together with their fold-change (in parentheses). Upregulated proteins are shown in bold.

Functional category	P-VALUE	Proteins
Purine metabolism	3.29E-04	Ade1p (0.27) Guk1p (0.38) Ado1p (0.39) Shm2p (0.54)
C-compound and carbohydrate metabolism	1.27E-06	Tdh3p (3.2–4.2) Tdh2p (2.8–6.9) Pgk1p (3.6) Eno1p (2.5) Adh1p (13.0) YDL124wp (0.28) Sec53p (0.39) Dys1p (0.41) Eno2p (0.46) Shm2p (0.54) Rki1p (0.40) Idh2p (0.47) Ald6p (0.56)
Energy	188E-05	Tdh3p (3.2–4.2) Tdh2p (2.8–6.9) Pgk1p (3.6) Eno1p (2.5) Adh1p (13.0) Pdb1p (0.35) Eno2p (0.46) Rki1p (0.40) Idh2p (0.47) Ald6p (0.56)
Glycolysis and gluconeogenesis	6.69E-07	Tdh3p (3.2–4.2) Tdh2p (2.8–6.9) Pgk1p (3.6) Eno1p (2.5) Pdb1p (0.35) Eno2p (0.46)
Fermentation	2.76E-02	Adh1p (13.0) Ald6p (0.56)
Protein synthesis	1.45E-02	Rps10bp (> 10) Efb1p (0.53) Tma19p (0.36) Mrp8p (0.28) Rps0bp (0.54) Hcr1p (0.30) Ssb2p (0.10)
Stress response	9.99E-02	Cpr1p (0.41–0.47) Hmf1p (0.53) Sod1p (0.41) Ahp1p (0.2–0.45) Ssb2p (0.10)
Oxidative stress response	3.69E-02	Sod1p (0.41) Ahp1p (0.2–0.45)
Homeostasis of cations	5.97E-02	Sod1p (0.41) Ahp1p (0.2–0.45) Vma4p (0.39)