Table I.
Group 1 | Group 2 | Group 3 | Group 4 | Group 5 | IFG | P for trend | |
---|---|---|---|---|---|---|---|
FG values (Mg %) | 50–79 | 80–84 | 85–89 | 90–94 | 95–99 | 100–125 | |
Mean FG (Mg %) | 74.4 | 82.1 | 87 | 92 | 97 | 106 | – |
n | 2017 | 2065 | 2317 | 1837 | 1451 | 1226 | – |
Mean follow-up (y) | 4.3 | 4.3 | 4.3 | 4.4 | 4.3 | 4.2 | – |
Age | 48 | 49 | 50 | 50.7 | 52 | 54.7 | <.001 |
Male gender | 61.1% | 67.2% | 74.1% | 77.3% | 79.3% | 83.1% | <.001 |
BMI | 24.6 | 25.4 | 26 | 26.5 | 27 | 27.6 | .1 |
SBP | 123 | 125 | 127 | 129 | 130 | 134 | <.001 |
TG | 91 | 99 | 107 | 113 | 117 | 132 | <.001 |
LDL | 121 | 123 | 124 | 126 | 125 | 126 | <.001 |
HDL | 51 | 50 | 49 | 47 | 47 | 45 | <.001 |
Smoking | 21.6% | 18.3% | 15.7% | 14.5% | 14.1% | 10.9% | <.001 |
Family history | 30.1% | 32.5% | 32.8% | 33.0% | 33.7% | 34.4% | .02 |
A total of 10,913 men and women were divided according to glucose levels to 5 groups (50–79, 80–84, 85–89, 90–94, and 95–99 mg/dL) plus an IFG group (100–125 mg/dL). Cardiovascular disease risk factors (age, male gender, systolic blood pressure [SBP], and family history of CVD, TG, LDL cholesterol, and BMI levels) were more likely to increase across the entire range of fasting glucose level. The percentage of smokers (current) and HDL cholesterol levels inversely correlated with fasting glucose levels.
Triglyceride and HDL were log transformed; SBP, TG, LDL, HDL are adjusted for age.