Fig 2.

Effect of modified radiotherapy (RT) versus conventional RT on overall survival, by RT types in non–small-cell lung cancer trials. Each trial is represented by a blue square, the center of which denotes the hazard ratio (HR) for that trial comparison, with the horizontal lines showing the 95% CIs. The size of the square is directly proportional to the amount of information contributed by the trial. The gold diamonds represent pooled HRs for the trial groups and the blue diamond the overall HRs, with the center denoting the HR and the extremities the 95% CI. The fixed effect model was used. CHART, Continuous Hyperfractionated Accelerated Radiation Therapy; CHARTWEL, CHART Week-End Less; CT, chemotherapy; Conv., conventional; ECOG, Eastern Cooperative Oncology Group; Exp., experimental; NCCTG, North Central Cancer Treatment Group; O-E, observed-expected; PCMI, Peter MacCallum Institute; RTOG, Radiation Therapy Oncology Group.