Figure 1:

Mean ± standard deviation of estimates for, A, B, axon diameter; C, D, restricted fraction; E, F, free water fraction; and, G, H, axon density in the six healthy control subjects and six patients with MS within ROIs drawn in NAWM in the genu, body, and splenium of the midline sagittal section of the corpus callosum in the patients with MS and in similar locations in the healthy control subjects. The estimates for axon diameter (B), restricted fraction (D), free water fraction (F), and axon density (H) within the lesion for each patient with MS are indicated as bars with hatch marks and are color coded to match the location of the corresponding normal-appearing areas of the corpus callosum.