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Sagittal FLAIR images (top row) and voxelwise maps of axon diameter (second row), restricted fraction (third row), and axon density (bottom row) in the midline corpus callosum in the six patients with MS. Lesions can be seen on FLAIR images (red arrows) and voxelwise maps (white arrows). Lesions show increased axon diameter and decreased restricted fraction and axon density, as compared with the adjacent NAWM.
