Table 2.
Peripheral blood cell counts and inflammation parameters of healthy subjects and COPD patients
| Blood cells and biomarkers | Healthy subjects (n=35) | COPD patients (n=51) |
|---|---|---|
| Total leukocytes (×103/µL) | 6.2 (4.5–9.4) | 8.2*** (3.6–17.8) |
| Neutrophils (%) | 53.3 (33.9–66) | 59.0** (37.3–93.7) |
| Lymphocytes (%) | 36.1 (24.2–55.4) | 27.3*** (4.5–46.4) |
| Monocytes (%) | 8.0 (4.3–15.3) | 8.0 (0.8–13.2) |
| Eosinophils (%) | 2.0 (0.5–8.9) | 2.2 (0–9.1) |
| Basophils (%) | 0.5 (0.2–1.2) | 0.5 (0–1.6) |
| Neutrophils (per mm3) | 3,127 (4–18,659) | 4,791*** (2,305–15,252) |
| Lymphocytes (per mm3) | 2,211 (1,250–4,266) | 2,245 (491–3,799) |
| Monocytes (per mm3) | 504 (249–848) | 680** (68–1,443) |
| Eosinophils (per mm3) | 114 (28–510) | 168 (0–569) |
| Basophils (per mm3) | 31 (9–263) | 36 (0–89) |
| Fibrinogen (g/L) | 2.9 (2.0–4.4) | 3.5*** (2.3–7.0) |
| C-reactive protein (mg/L) | 1.1 (0–6.2) | 3.4*** (0–122.2) |
Notes: Data are presented as median (range).
**
P<0.01,
***
P<0.001 vs healthy subjects.