Table S1.
PRO-Morning COPD Symptoms Questionnaire
| PRO-Morning COPD Symptoms Questionnaire: pre-morning dose assessment | |
| Please rate the severity of your shortness of breath when you woke up today | 0–10 Numeric Rating Scale (0= no shortness of breath to 10= shortness of breath as bad as you can imagine) |
| Please rate the difficulty you had clearing the phlegm/mucus from your lungs when you woke up today | 0–10 Numeric Rating Scale (0= no phlegm/mucus to 10= as difficult as you can imagine) |
| Please rate the severity of your chest tightness when you woke up today | 0–10 Numeric Rating Scale (0= no chest tightness to 10= chest tightness as bad as you can imagine) |
| Please rate the severity of your wheezing when you woke up today | 0–10 Numeric Rating Scale (0= no wheezing to 10= wheezing as bad as you can imagine) |
| Please rate the severity of your coughing when you woke up today | 0–10 Numeric Rating Scale (0= no coughing to 10= coughing as bad as you can imagine) |
| Please rate how bothered you were by your COPD symptoms when you woke up today | 0–10 Numeric Rating Scale (0= no bother to 10= bothered as bad as you can imagine) |
| PRO-Morning COPD Symptoms Questionnaire: post-morning dose assessment: to be answered approximately 3 hours after morning medication | |
| Please rate the severity of your shortness of breath as you feel now | 0–10 Numeric Rating Scale (0= no shortness of breath to 10= shortness of breath as bad as you can imagine) |
| Please rate the difficulty you had clearing the phlegm/mucus as you feel now | 0–10 Numeric Rating Scale (0= no phlegm/mucus to 10= as difficult as you can imagine) |
| Please rate the severity of your chest tightness as you feel now | 0–10 Numeric Rating Scale (0= no chest tightness to 10= chest tightness as bad as you can imagine) |
| Please rate the severity of your wheezing as you feel now | 0–10 Numeric Rating Scale (0= no wheezing to 10= wheezing as bad as you can imagine) |
| Please rate the severity of your coughing as you feel now | 0–10 Numeric Rating Scale (0= no coughing to 10= coughing as bad as you can imagine) |
| Please rate how bothered you feel now by your COPD symptoms | 0–10 Numeric Rating Scale (0= no bother to 10= bothered as bad as you can imagine) |
Abbreviations: COPD, chronic obstructive pulmonary disease; PRO, patient reported outcome.