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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: Antiviral Res. 2016 Apr 21;131:100–108. doi: 10.1016/j.antiviral.2016.04.001

Figure 2. Induction of heterosubtypic inhibitory antibodies.

Figure 2

Mice (5/grp) were immunized with either PBS, rH1CA + GLA-SE, or rH5VN + GLA-SE, and serum collected on day 42 was assayed for cross-inhibitory Abs by HAI. The viruses tested included clade 1 viruses A/Vietnam/1194/2004 (H5N1) (panel a) and A/Cambodia/RO405050/2007 (H5N1) (panel b), clade 2.2 virus A/turkey/Turkey/1/2005 (H5N1) (panel c), clade 2.3.4 virus A/H5N1/Anhui/1/05 (H5N1) (panel d), or the H1N1 virus A/California/07/09 (H1N1) (panel e).