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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: Kidney Int. 2016 Mar 24;90(1):67–76. doi: 10.1016/j.kint.2016.01.022

Figure 2. Renal morphologic injury induced by ischemia– reperfusion under control conditions or with FeS+SnPP administration.

Figure 2

By 18 hrs post ischemia-reperfusion, extensive proximal tubule necrosis and cast formation in the inner cortex/outer medullary stripe were observed in unconditioned mice (panel A). The extent of that injury was markedly reduced in FeS+SnPP conditioned mice (panel B). The scale bar = 200 microns. The extent of injury was graded on a scale of 1-4+ (least to most severe injury observed), and was significantly decreased by FeS+SnPP pre-treatment (3.5±0.3; 1.5±0.3; <0.01).