FIG 9.

SBVp32 virulence is related to increased virus replication in IFNAR^−/− mice. (A) Groups of 5 mice were inoculated intraperitoneally (1,000 PFU), and weight was recorded over a 15-day period. The area under the curve was estimated for each mouse and then compared among groups (P < 0.05 [as determined by analysis of variance and a Tukey multiple-comparison test]). (B) Representative micrographs displaying the pathological changes observed in SBVp32-infected IFNAR^−/− mice (left) and the presence of viral RNA by ISH (right).