TABLE 2.

Top 20 downregulated genes in BTV-infected compared to mock-infected A549 cells

Gene	BTV8ΔNS4 vs. mock infected		BTV8wt vs. mock infected
	Ranka	Fold change	Rank	Fold change
CLDND2	D1	0.13	D157	0.30
CPN1	D2	0.13	D24	0.20
DHRS4L1	D3	0.14	D425	0.38
EMID1	D4	0.14	NAb	1.0
LOC100506229	D5	0.16	D3	0.15
HMOX1	D6	0.16	D4	0.15
KRT82	D7	0.16	D73	0.26
SHH	D8	0.17	D5	0.15
NUPR1	D9	0.18	D11	0.18
KRT4	D10	0.18	D142	0.30
SFRP4	D11	0.19	D9	0.17
NRTN	D12	0.19	NA	1.0
EMILIN1	D13	0.20	D18	0.20
LOC113230	D14	0.20	NA	1.0
LINC00086	D15	0.20	D329	0.36
OSGIN1	D16	0.21	D10	0.18
KLHDC7A	D17	0.21	D1	0.12
ATOH8	D18	0.22	D2	0.14
MIR210HG	D19	0.22	D106	0.28
KRTAP4-1	D20	0.22	D27	0.21

^aRanks of downregulated genes. The numbers D1, D2, etc. refer to the rank of the specified gene (the most downregulated gene under a given condition is ranked first).

^bNA, not applicable, as the genes were not found to be differentially expressed in the samples considered.