Fig. 1.

Suggested treatment algorithm based on risk assessment and degree of protein excretion. ¹ Initiate low-salt diet; start ACE inhibitors/ARB (target blood pressure <130/80 mm Hg) as tolerated. ² If the patient relapses, consider immunosuppressive therapy. ³ Initial treatment with an appropriate immunosuppressive agent after excluding contraindications to treatment, such as infections, malignancy and impaired GFR.