Table 4.
Treatment effect size on forearm and whole body muscle protein metabolism at week 12
| Difference Between Groups at 12 Weeksa (95% CI) | Difference Between Groups at 12 Weeksb (95% CI) | |
|---|---|---|
| Forearm muscle protein metabolism (μg/100 ml per min) | ||
| Protein synthesis | −37 (−126 to 45) | −25 (−163 to 87) |
| Protein breakdown | c−57 (−93 to −27) | c−46 (−102 to −1) |
| Net balance | 24 (−32 to 71) | −2 (−94 to 69) |
| Whole body protein metabolism (mg/kg per fat free mass per min) | ||
| Protein synthesis | −0.1 (−0.6 to 0.4) | 0.2 (−0.4 to 1.1) |
| Protein breakdown | −0.2 (−0.6 to 0.2) | 0.2 (−0.5 to 0.9) |
| Net Balance | 0.08 (−0.01 to 0.16) | 0.06 (−0.09 to 0.17) |
a
Multivariable linear regression model was used to estimate difference between groups on outcomes at week 12 after adjusting for baseline values only.
b
Multivariable linear regression model was used to estimate difference between groups at week 12 after adjusting for baseline values, age, sex, race, hs-CRP, diabetes and fat mass through the logit of propensity score. 95% CI was calculated using bootstrap resampling.
c
The effect was statistically significant.