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. 2016 Apr 26;11(7):1245–1259. doi: 10.2215/CJN.06660615

Table 1.

Baseline characteristics and geriatric impairments

Baseline Characteristics Study Setting and Design Geriatric Impairments Assessed
Authors Year of Publication No. of Patients Age, yr (SD/range) Dialysis Modality Setting Planned Start Only Exclusion Criteria P/R Median/Mean Follow-Up, moa Cognition Mood ADL Performance Mobility Nutrition Frailty
Inclusion at initiation of dialysis
 Alfaadhel et al. (17) 2015 390 63 (15) HD, PD Monocenter AKI, dialysis <1 wk in own dialysis center P 20 (11–34)b +
 Arai et al. (18) 2014 202 80 (4) HD, PD Monocenter None R 6c +
 Chandna et al. (22) 1999 292 61 (18–92) HD, PD Monocenter AKI P +
 Churchill et al. (43) 1996 680 54 (18–82) PD Multicenter x Early deaths/transplant (<6 mo), HIV, hepatitis B positive, active inflammatory disease P 24c + +
 Couchoud et al. (25)d,e 2009 2500 81 (4) HD, PD Database (REIN 2002–2006) Acute renal failure, <75 yr old R 6c + +
 Couchoud et al. (26)d 2015 12,500 81 (?) HD, PD Database (REIN 2005–2012) Acute renal failure, <75 yr old R 3c + +
 Doi et al. (28) 2015 688 69 (59–77) HD Multicenter (UMINCTR) x No predialysis care, withdrawal within 1 yr, eGFR>10 at start of dialysis R 12c +
 Genestier et al. (29) 2009 122 81 (4) PD Monocenter x ≤75 yr old R 18 (?) + + + +
 Jassal et al. (31) 1996 99 65 (41–90) HD Monocenter AKI P ? + + + +
 Joly et al. (33)f 2003 107 82 (3) HD Monocenter Patients <80 yr old, AKI P 100c +
 Kim et al. (34)g 2014 410 72 (5) HD, PD Database (CRC for ESRD) AKI, <65 yr R 60c + +
 Mauri et al. (38)d 2008 3455 65 (14) HD Database (RMRC) No minimum follow-up of 1 yr R 12c +
 Rakowski et al. (40) 2006 272,024 63(?) HD, PD Database (USRDS 1995–1999) None R 24c + +
 Soucie et al. (41)d 1996 15,245 57 (16) HD, PD Database (Network 6) Nonwhite or black patients R 3c + +
 Thamer et al. (42) 2015 52,796 77 (7) HD, PD Database (USRDS 2009–2010) Did not have 2-yr previous Medicare claims history, <67 yr old R 6c +
Inclusion after initiation of dialysis
 Bao et al. (19) 2012 1576 60 (14) HD, PD Database USRDS 2005–2007 AKI R 35 (?) +
 Boulware et al. (20) 2006 917 ? (19–95) HD, PD Database (CHOICE Study) x None R 18 (2–24)b +
 Chilcot et al. (23) 2011 160 57 (16) HD, PD Three centers x No visual, physical, or cognitive (MMSE<22) impairment P 17 (2–34) + +
 Chan et al. (21) 2012 167 65 (14) HD, PD Monocenter x AKI, early transplant, early transfer other unit R 53 (23–83) +
 Chung et al. (24) 2009 219 54(13) PD Monocenter x None P 23 (±10) +
 Diefenthaeler et al. (27) 2008 40 55 (15) HD Monocenter x MMSE<18, blindness, illiteracy P 11 (5–22) +
 Honda et al. (30) 2007 328 53 (12) HD, PD Monocenter x ≥70 yr old, overt infection, acute vasculitis, liver disease P 21 (1–72) +
 Johansen et al. (32) 2007 2275 58 (16) HD, PD Database (Dialysis Wave II Study) None R 12c +
 Lacson et al. (35) 2012 6415 62 (15) HD Multicenter (FMCNA) None R 12c +
 Lacson et al. (36)h 2013 8776 62 (15) HD Multicenter (FMCNA) None R 12c +
 Lopez Revuelta et al. (37) 2004 318 60 (?) HD Multicenter AKI, severe physical or psychiatric impairments P 26 (0–42) +
 McClellan et al. (39) 1991 294 57 (15) HD, PD Multicenter None P 16 (1–19) + +

P, prospective cohort study; R, retrospective cohort study; ADL, activity of daily living; HD, hemodialysis; PD, peritoneal dialysis; +, addressing this geriatric impairment; REIN, Ramipril Efficacy in Nephropathy; ?, not reported; UMINCTR, University Hospital Medical Information Network Clinical Trials Registry; CRC for ESRD, Clinical Research Center for End Stage Renal Disease; RMRC, Registre de Malalts Renals de Catalunya; USRDS, US Renal Database System; CHOICE, Choices for Healthy Outcomes in Caring for; MMSE, Mini Mental State Examination; FMCNA, Fresenius Medical Care North America.

a

If mean is reported, SD is in parentheses; if median is reported, range is in parentheses.

b

Interquartile range instead of range.

c

Total study follow-up.

d

Data of development/training cohort only.

e

Small overlap of patients of the two cohorts in works by Couchoud et al. (25,26) (years 2005–2006, with a maximum potentially overlap of 20%).

f

Data of the dialysis cohort only.

g

Data of the ≥65 years old cohort only. Early deaths (unless otherwise described) are <3 months.

h

Important overlap of the two cohorts in the works by Lacson et al. (35,36).