Table 5.
The relation of geriatric impairment with hospitalization
| Geriatric Impairment and Authors | Relation with Hospitalization | Outcome | Adjusted for in Multivariate Analysis (if Applicable) | |||
|---|---|---|---|---|---|---|
| Univariate | Multivariate | |||||
| HR/RR/OR (95% CI) | P Value | HR/RR/OR (95% CI) | P Value | |||
| Depression | ||||||
| Lacson et al. (36) | — | <0.001 | 1.13 (1.02 to 1.25) | 0.02 | Hospitalization rate | Age, sex, race, DM, albumin, creatinine, hemoglobin, calcium, phosphorus, transferrin saturation, SF-36 PCS, SF-36 MCS (two mental health items of interest removed), dialysis vintage |
| Lacson et al. (36) | — | <0.001 | 1.20 (1.07 to 1.35) | 0.002 | Duration of hospitalization | Age, sex, race, DM, albumin, creatinine, hemoglobin, calcium, phosphorus, transferrin saturation, SF-36 PCS, SF-36 MCS (two mental health items of interest removed), dialysis vintage |
| Performance | ||||||
| Churchill et al. (43) (≤80 versus >80) | — | — | 1.63 (—) | <0.05 | Duration of hospitalization | Age, sex, KPS, CVD, DM, albumin, malnutrition, CCr, Kt/V, β2M, country |
| Lopez Revuelta et al. (37) | 1.25 (1.05 to 1.48)a | 0.01 | 1.12 (0.92 to 1.36)a | 0.51 | Duration of hospitalization | KPS, CCI, logarithmic time, hospital, SF-36 PCS, SF-36 MCS |
| Malnutrition | ||||||
| Churchill et al. (43) | — | — | 0.82 (—)b | <0.05 | Duration of hospitalization | Age, sex, KPS, CVD, DM, albumin, CCr, Kt/V, β2M, country |
| Frailty | ||||||
| Bao et al. (19) | 1.44 (1.26 to 1.66) | <0.001 | 1.26 (1.09 to 1.45) | <0.001 | Time to first hospitalization | Age, sex, race, smoking, comorbidities, Medicaid versus other payer, eGFR, albumin, hemoglobin, dialysis modality, erythropoietin use, early nephrology referral |
| Johansen et al. (32) | 1.90 (1.67 to 2.17) | <0.05 | 1.56 (1.36 to 1.79) | <0.05 | Time to first hospitalization or death | Age, sex, race, BMI, albumin, dialysis modality, comorbidities, employment status, marital status, smoking |
| Johansen et al. (32) | — | — | 1.98 (1.41 to 1.87) | <0.05 | Time to first nonvascular–related hospitalization or death | Age, sex, race, BMI, albumin, dialysis modality, comorbidities, employment status, marital status, smoking |
HR, hazard ratio; RR, relative risk; OR, odds ratio; 95% CI, 95% confidence interval; —, not mentioned; DM, diabetes mellitus; SF-36 PCS, Short–Form (36) Health Survey Physical Component Score; SF-36 MCS, Short–Form (36) Health Survey Mental Component Score; KPS, Karnofsky performance score; CVD, cardiovascular disease; CCr, creatinine clearance; β2M, β2-microglobulin; CCI, Charlson Comorbidity Index.
a
Risk per increase in score of 10.
b
Risk per point increase.