Table 1.
Baseline characteristics of patients undergoing parathyroidectomy because of secondary hyperparathyroidism in the United States from 2002 to 2011
| Variables | 2002 | 2003 | 2004 | 2005 | 2006 | 2007 | 2008 | 2009 | 2010 | 2011 | All | P Value |
| N | 3737 | 4210 | 3287 | 1890 | 3225 | 3368 | 3564 | 2908 | 3288 | 3496 | 32,971 | |
| Age, yr, median (IQR) | 50 (40–60) | 50 (40–60) | 50 (40–59) | 50 (37–61) | 49 (39–61) | 53 (41–63) | 52 (41–63) | 51 (40–62) | 53 (41–65) | 53 (42–66) | 51 (40–62) | <0.001 |
| Age, yr, % | ||||||||||||
| 0–19 | 1.1 | 1.2 | 1.5 | 1.3 | 1.3 | 1.0 | 1.6 | 1.2 | 1.4 | 1.0 | 1.3 | 0.98 |
| 20–44 | 36.3 | 33.6 | 31.2 | 36.6 | 36.2 | 29.9 | 30.3 | 34.8 | 30.4 | 28.9 | 32.6 | 0.004 |
| 45–64 | 45.0 | 47.7 | 52.4 | 44.2 | 42.3 | 47.2 | 44.7 | 42.1 | 41.6 | 41.4 | 45.0 | 0.001 |
| 65+ | 17.5 | 17.5 | 14.9 | 17.9 | 20.2 | 22.0 | 23.3 | 21.9 | 26.6 | 28.6 | 21.1 | <0.001 |
| Men, % | 45.3 | 48.2 | 45.5 | 49.3 | 45.5 | 49.9 | 43.3 | 42.8 | 46.6 | 46.1 | 46.0 | 0.31 |
| Region, % | ||||||||||||
| Northeast | 19.2 | 16.6 | 13.3 | 18.6 | 17.3 | 12.7 | 23.0 | 15.5 | 15.2 | 13.7 | 16.5 | 0.64 |
| Midwest | 22.2 | 21.4 | 26.6 | 21.4 | 19.6 | 24.3 | 18.7 | 20.2 | 21.6 | 23.6 | 22.0 | 0.85 |
| South | 37.1 | 41.6 | 38.4 | 39.9 | 41.3 | 41.2 | 35.8 | 44.9 | 46.9 | 46.6 | 41.3 | 0.21 |
| West | 21.4 | 20.4 | 21.7 | 20.1 | 21.9 | 21.8 | 22.5 | 19.3 | 16.3 | 16.1 | 20.2 | 0.24 |
| Hospital status, % | ||||||||||||
| Rural | 3.7 | 3.9 | 3.5 | 3.1 | 2.6 | 3.6 | 3.9 | 5.0 | 4.0 | 1.4 | 3.5 | 0.62 |
| Urban nonteaching | 27.2 | 27.1 | 26.4 | 35.3 | 27.4 | 35.3 | 28.1 | 29.1 | 29.6 | 32.0 | 29.4 | 0.37 |
| Urban teaching | 69.1 | 69.0 | 70.1 | 61.6 | 70.0 | 61.1 | 68.0 | 65.9 | 66.3 | 66.6 | 67.1 | 0.47 |
| Payer, % | ||||||||||||
| Medicare | 77.0 | 80.9 | 79.0 | 75.6 | 77.2 | 77.7 | 79.0 | 79.6 | 78.2 | 79.6 | 78.6 | 0.75 |
| Medicaid | 5.0 | 4.9 | 5.8 | 8.2 | 6.7 | 5.9 | 5.5 | 7.9 | 6.7 | 6.2 | 6.1 | 0.11 |
| Private | 17.0 | 13.0 | 13.4 | 15.7 | 14.4 | 13.4 | 13.6 | 10.8 | 13.2 | 12.5 | 13.7 | 0.04 |
| Other | 1.0 | 1.2 | 1.3 | 0.5 | 1.6 | 3.0 | 1.8 | 1.4 | 1.8 | 1.7 | 1.6 | 0.05 |
| Comorbidities, % | ||||||||||||
| Diabetes | 22.0 | 26.1 | 22.9 | 24.5 | 25.8 | 28.6 | 24.5 | 29.2 | 32.2 | 32.6 | 26.8 | <0.001 |
| Hypertension | 79.2 | 85.2 | 85.8 | 84.6 | 85.6 | 87.4 | 90.2 | 87.7 | 91.6 | 91.2 | 86.8 | <0.001 |
| Heart failure | 7.9 | 11.8 | 10.3 | 11.1 | 10.7 | 10.4 | 11.1 | 10.0 | 12.5 | 15.1 | 11.1 | 0.003 |
| Cerebrovascular disease | 1.6 | 1.0 | 1.4 | 1.2 | 1.3 | 1.2 | 1.5 | 1.2 | 1.3 | 1.9 | 1.4 | 0.72 |
| Peripheral vascular disease | 4.5 | 7.2 | 4.3 | 7.4 | 5.6 | 6.7 | 5.9 | 5.8 | 5.7 | 6.1 | 5.9 | 0.58 |
| Prior fracture | 2.2 | 1.6 | 2.4 | 1.0 | 2.3 | 1.7 | 1.3 | 2.0 | 1.0 | 1.4 | 1.7 | 0.11 |
| Prior kidney transplant | 20.5 | 16.1 | 24.8 | 20.7 | 13.6 | 14.6 | 16.2 | 18.3 | 16.4 | 16.0 | 17.6 | 0.09 |
P value for linear trend across years was computed through logistic regressions using continuous year as the sole predictor. IQR, interquartile range.