Table 4.
All–cause mortality risk
| Variables | Hazard Ratio (95% CI) | P Value |
|---|---|---|
| Age, >58 versus ≤58 yr | 1.58 (1.10 to 2.28) | 0.01 |
| Sex, men versus women | 1.07 (0.73 to 1.56) | 0.53 |
| Diabetes mellitus, present versus absent | 1.56 (1.07 to 2.26) | 0.01 |
| Smoking, yes versus no | 1.10 (0.75 to 1.61) | 0.47 |
| SGA, malnourished versus well nourished | 2.28 (1.56 to 3.33) | <0.001 |
| eGFR, ≤6.9 versus >6.9 ml/min per 1.73 m2 | 1.42 (0.99 to 2.04) | 0.09 |
| Calendar year period, 2010–2014 versus 2006–2009 | 1.21 (0.62 to 2.37) | 0.66 |
| Calendar year period, 2010–2014 versus 2000–2005 | 0.83 (0.42 to 1.65) | 0.64 |
| Calendar year period, 2010–2014 versus 1994–1999 | 0.75 (0.37 to 1.56) | 0.58 |
| WBC, >8.0×103 versus ≤8.0×103/μl | 1.94 (1.34 to 2.82) | <0.001 |
| IL-6, >6.7 versus ≤6.7 pg/ml | 1.79 (1.20 to 2.67) | 0.01 |
| Troponin T, >0.06 versus ≤0.06 μg/L | 1.49 (1.03 to 2.16) | 0.14 |
| hsCRP, >6.4 versus ≤6.4 mg/L | 1.25 (0.80 to 1.95) | 0.42 |
| PLT, >261×103 versus ≤261×103/μl | 1.22 (0.85 to 1.75) | 0.30 |
| sVCAM-1, >1356 versus ≤1356 ng/ml | 1.15 (0.78 to 1.69) | 0.43 |
| sICAM-1, >249 versus ≤249 ng/ml | 1.07 (0.76 to 1.49) | 0.06 |
| Albumin, >3.3 versus ≤3.3 g/dl | 1.07 (0.75 to 1.55) | 0.59 |
| Ferritin, >122 versus ≤122 ng/ml | 0.96 (0.69 to 1.34) | 0.77 |
| IGF-1, >155 versus ≤155 μg/ml | 0.78 (0.54 to 1.14) | 0.27 |
| TNF, >12.1 versus ≤12.1 pg/ml | 0.65 (0.44 to 0.97) | 0.04 |
| Orosomucoid, >1.1 versus ≤1.1 g/L | 0.62 (0.41 to 0.95) | 0.07 |
The output from an imputed multivariate generalized linear model (GENMOD) of all–cause mortality hazard ratios (95% CIs) estimated during 60 months of follow-up calculated for each evaluated biomarker and adjusted for other variables. Patient outcomes were censored for renal transplantation. 95% CI, 95% confidence interval; SGA, subjective global assessment of nutritional status; WBC, white blood cell; hsCRP, high–sensitivity C–reactive protein; PLT, platelet count; sVCAM-1, soluble vascular cellular adhesion molecule 1; sICAM-1, soluble intracellular adhesion molecule.