Table 3. Ratio of 13C5-adenosine production with and without CD73 inhibition, pre-operation and prior to separation from cardiopulmonary bypass.
Pre-operative, mean [SD] | Rewarming, mean [SD] | Pre-operative to Rewarming Mean Difference (95% CI) | p-value | |
---|---|---|---|---|
Entire Cohort | 0.75 (0.09) | 0.68 (0.08) | 0.08 (0.05, 0.11) | <0.0001 |
Low Concentration 13C5-AMP | 0.72 (0.10) | 0.65 (0.09) | 0.07 (0.03, 0.10) | <0.005 |
High Concentration 13C5-AMP | 0.79 (0.07) | 0.70 (0.07) | 0.09 (0.04, 0.13) | <0.001 |