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PET/CT images of angiogenesis in murine model of hind limb ischemia. Animals were injected with 125I-labeled dendrimers 24 h before imaging. The PET signal is significantly greater in ischemic limb muscle imaged with αvβ3-targeted dendrimers (B) than in muscle imaged with nontargeted dendrimers (A). (Reprinted with permission of (9).)
