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. Author manuscript; available in PMC: 2016 Jul 6.
Published in final edited form as: Cell Rep. 2015 Nov 5;13(7):1444–1455. doi: 10.1016/j.celrep.2015.10.013

Figure 3. HSP90 stabilizes NELFA, and SAHA increases NELFA binding.

Figure 3

(A) NELFA stability after treatment with different elongation-affecting drugs, shown with western of BT474 cell lysates, representative image for one of two blots.

(B) Correlation of NELFA and HSP90 fold enrichments in promoter and gene body regions for 33119 annotated RefSeq genes. Two biological replicates for each ChIP-seq were conducted and average signal is plotted.

(C) Venn diagrams of RNAP2 and NELFA peak overlaps. Overlaps were within a 500 base pair window. Numbers of genes in each section are shown.