Table 3.

Adjusted logistic regression analyses of predictors of OSA (AHI ≥5)

Predictor	Analyses								Interactionf
	Malesa				Femalesb
	β	χ2	P-values	Odds ratio (95% CI)	β	χ2	P-values	Odds ratio (95% CI)
Age ≥45 (years)	1.28	6,382.6	P<0.001	3.58 (3.47–3.69)	1.62	9,941.3	P<0.001	5.06 (4.90–5.22)	P<0.001
Obese	0.52	901.2	P<0.001	1.69 (1.63–1.75)	0.27	250.6	P<0.001	1.31 (1.27–1.35)	P<0.001
Neck circumference (in)	0.22	1,156.1	P<0.001	1.24 (1.23–1.26)	0.20	1,395.6	P<0.001	1.22 (1.21–1.24)	P=0.30
Snoring	0.53	1,116.8	P<0.001	1.69 (1.64–1.75)	0.51	1,162.5	P<0.001	1.67 (1.62–1.72)	P=0.37
Witnessed apneas	0.59	669.4	P<0.001	1.81 (1.73–1.89)	0.40	253.2	P<0.001	1.49 (1.42–1.56)	P<0.001
Hypertension	0.31	357.0	P<0.001	1.37 (1.32–1.41)	0.42	697.5	P<0.001	1.52 (1.47–1.57)	P<0.001
Diabetes	0.11	20.9	P<0.001	1.12 (1.07–1.18)	0.09	17.7	P<0.001	1.09 (1.05–1.14)	P=0.44
Heart disease	0.29	121.8	P<0.001	1.34 (1.27–1.41)	0.24	84.3	P<0.001	1.27 (1.20–1.33)	P=0.07

Notes:

^aMales – overall model was significant (χ² [9, 149,071]=17,292.8, P<0.001) and accounted for 18.1% of the variance in OSA (AHI ≥5);

^bFemales – overall model was significant (χ² [9, 1,12,794]=20,628.4, P<0.001) and accounted for 23.6% of the variance in OSA (AHI ≥5). Waking choking was not statistically significant (males P=0.15; females P=0.05).

^fInteraction =sex × predictor. For obese: body mass index ≥30 kg/m². For snoring and witnessed apneas: % answer “at least frequently [3–4 times per week]” to “on average in the past month, how often have you snore or been told that you snore […] have you ever been told that you stop breathing in your sleep or wake up choking or gasping?”. For hypertension, diabetes, and heart disease: % endorsed yes to “have you been diagnosed or treated for any of the following conditions?”.

Abbreviations: AHI, apnea hypopnea index; CI, confidence interval; OSA, obstructive sleep apnea.