Table 1.
Common medications associated with liver failure.
| Drug class | Pattern of drug-induced liver injury (DILI) |
|---|---|
| Antibiotics | |
| Amoxicillin/clavulanate | Cholestasis2 |
| Isoniazid | Hepatocellular2 |
| Nitrofurantoin | Mixed2 |
| Rifampin | Hepatocellular2 |
| Trimethoprim-sulfamethoxazole | Mixed2 |
| Anticonvulsants | |
| Carbamazepine | Mixed2 |
| Valproic acid | Hepatocellular2 |
| Antihypertensives | |
| Labetalol | Hepatocellular4 |
| Methyldopa | Hepatocellular5–10 |
| Analgesics | |
| Acetaminophen | Hepatocellular2 |
| Acetysalicyclic acid, other NSAIDs | Hepatocellular2 |
| Anti-thyroid medications | |
| Amiodarone | Hepatocellular2 |
| Other | |
| Azathioprine | Mixed2 |
| Chemotherapy | – |
| Herbal medications | – |
| Methotrexate | Hepatocellular2 |