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. Author manuscript; available in PMC: 2017 Apr 21.
Published in final edited form as: Nature. 2016 Apr 13;532(7599):385–388. doi: 10.1038/nature17436

Figure 1. Evolution of CRISPR-mediated immunity leads to rapid extinction of virus.

Figure 1

a, b, Titre (in plaque-forming units per millilitre) of virus DMS3vir over time upon infection of wild-type (WT) P. aeruginosa (a) and P. aeruginosa strain csy3::LacZ (b) (CRISPR KO strain). Each line indicates a biological replicate experiment (n = 6). The limit of detection is 200 p.f.u. ml−1.