Table 1.

Relationship between CXCL16 and CXCR6 expression in situ and clinicopathological parameters of patients with GIST

Clinicopathological features	CXCL16					CXCR6
	n	Low	High	χ2	P-value	Low	High	χ2	P-value
Sex				0.17	0.674			0.18	0.673
Female	14	6	8			7	7
Male	29	9	20			11	18
Age (years)				0.89	0.344			0.00	0.937
<55	20	5	15			8	12
≥55	23	10	13			10	13
Tumor size				0.14	0.709			2.74	0.245
<10 cm	17	7	10			4	13
≥10 cm	26	8	18			14	12
Tumor number				0.08	0.776			1.73	0.189
Single	9	3	6			6	3
Multiple	34	12	22			12	22
Histology				0.06	0.972			0.91	0.634
Spindle	9	3	6			5	4
Epithelioid	15	5	10			6	9
Mixed	19	7	12			7	12
Mitotic index (per 50 HPFs)				2.32	0.128			0.63	0.428
<5	15	8	7			8	7
≥5	28	7	21			10	18
Tumor necrosis				0.00	0.957			1.33	0.249
−	27	10	17			9	18
+	16	5	11			9	7
Tumor bleeding				0.28	0.597			8.48	0.004
−	22	9	13			4	18
+	21	6	15			14	7
Surrounding tissue invasion				3.27	0.071			4.14	0.042
−	21	4	17			5	16
+	22	11	11			13	9

Note: Data in bold indicates statistical significance.

Abbreviations: GIST, gastrointestinal stromal tumors; HPFs, high power fields.