Table 2.
Correlations of TGF-β1 and CD163 expressions with clinicopathologic characteristics of gastric cancer patients
Variable | n | TGF-β1
|
CD163
|
||||
---|---|---|---|---|---|---|---|
High | Low | P-value | High | Low | P-value | ||
Sex | 0.738 | 0.623 | |||||
Male | 125 | 79 | 46 | 68 | 57 | ||
Female | 53 | 32 | 21 | 26 | 27 | ||
Age (years) | 0.536 | 0.548 | |||||
≤60 | 94 | 61 | 33 | 42 | 42 | ||
>60 | 84 | 50 | 34 | 52 | 42 | ||
Tumor size (cm) | 0.015 | 0.020 | |||||
<3 | 44 | 22 | 22 | 17 | 27 | ||
3–5 | 54 | 30 | 24 | 26 | 28 | ||
>5 | 80 | 59 | 21 | 51 | 29 | ||
Borrmann | 0.032 | 0.029 | |||||
I | 22 | 11 | 11 | 10 | 12 | ||
II | 55 | 32 | 23 | 21 | 34 | ||
III | 62 | 36 | 26 | 38 | 24 | ||
IV | 39 | 32 | 7 | 25 | 14 | ||
Differentiation | <0.001 | <0.001 | |||||
High | 12 | 3 | 9 | 3 | 9 | ||
Moderate | 57 | 24 | 33 | 20 | 37 | ||
Poor | 109 | 84 | 25 | 71 | 38 | ||
Depth of invasion | 0.033 | 0.002 | |||||
T1 | 16 | 5 | 11 | 5 | 11 | ||
T2 | 18 | 10 | 8 | 3 | 15 | ||
T3 | 67 | 47 | 20 | 39 | 28 | ||
T4 | 77 | 49 | 28 | 47 | 30 | ||
Lymph node metastasis | <0.001 | <0.001 | |||||
N0 | 49 | 18 | 31 | 13 | 36 | ||
N1 | 36 | 17 | 19 | 13 | 23 | ||
N2 | 35 | 26 | 9 | 11 | 13 | ||
N3 | 58 | 50 | 8 | 46 | 12 | ||
Distant metastasis | 0.003 | 0.019 | |||||
M0 | 138 | 78 | 60 | 66 | 72 | ||
M1 | 40 | 33 | 7 | 28 | 12 | ||
TNM stage | 0.002 | <0.001 | |||||
I | 21 | 8 | 13 | 5 | 16 | ||
II | 34 | 17 | 17 | 10 | 24 | ||
III | 83 | 53 | 30 | 51 | 32 | ||
IV | 40 | 33 | 7 | 28 | 12 |
Abbreviations: TGF, transforming growth factor; TNM, tumor node metastasis.