Fig. 2.

Host physiology associated with high-intensity interval training (HIIT) in HFD-fed mice. Weekly body mass in HFD-fed mice that were HIIT 3 times a week or untrained (A; n = 8 mice per group). Time to exhaustion (B) and running speed at exhaustion (C) during a graded treadmill exercise test in HFD-fed mice exercise trained for 6 wk vs. untrained mice. Epididymal adipose tissue mass in HFD-fed mice exercise trained for 6 wk or untrained (D). Blood glucose (E) and cumulative area under the curve (AUC; F) during insulin tolerance test (ITT; 1 IU/kg) in HFD-fed mice exercise trained for 6 wk or untrained. Data are means ± SE. *P < 0.05 vs. untrained. Nos. of mice analyzed for each condition are shown in brackets.