Fig. 4.

Genus level changes of gut microbiota associated with repeated exercise. Average relative abundance of genera in various gut segments of HFD-fed untrained and exercise-trained mice (A). OTUs significantly different in microbiota from any gut segment are shown from exercise-trained vs. untrained HFD-fed mice (B–E). Significant differences are noted in boldface for taxonomic classification in duodenum plus jejunum (A), ileum (B), cecum (C), and colon (D). A: data are mean values; B–E: data are box-and-whisker plots. *P < 0.05 trained vs. untrained. Nos. of mice analyzed for each condition are shown in brackets.