Fig. 1.

In utero exposure to laboratory-generated, combustion-derived particular matter (MCP230) results in increased body size. A: schematic of the experimental design. B: body weight throughout the high-fat diet phase of the intervention. C–E: absolute body fat (C), fat-free mass (D), and %body fat (E) after 12 wk of high-fat diet Zeitgerber time (ZT)12. Data shown are group means ± SE. §P < 0.05 via mixed linear model, compared by χ² test (B); *P < 0.05 via Student's t-test (C and D). Black bars, saline-exposed mice; gray bars, MCP230-exposed mice.