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Rab25 knockdown promotes CaV1.2 channel degradation. A: representative Western Blots illustrating effects of Rab25 knockdown on CaV1.2 and KV2.1 total protein. B: mean data, n = 4 for each. *P < 0.05 vs. scrm. C: representative Western blots illustrating effects of Rab25 knockdown on CaV1.2 total protein and regulation by bafilomycin (100 nM, 24 h) or MG132 (10 μM, 24 h). D: mean data, n = 3. *P < 0.05, compared with scrambled controls. #P < 0.05, compared with Rab25siRNA.
