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. 2015 Jun;240(6):760–773. doi: 10.1177/1535370215579167

Figure 2.

Figure 2

A schematic overview of prosurvival signals elicited by the activation of TRAIL receptors. With agonists binding to TRAIL-R1/R2, a secondary complex can be formed after receptor activation, leading to the activation of various signaling pathways that are involved in induction of nonapoptotic responses as indicated. (A color version of this figure is available in the online journal.)