Table 1.

Tyrosine phosphorylation of WW domain proteins and WW binding proteins

Protein	WW domain class	Residues modified	Kinase	Tyrosine phosphorylation in WW domain	Reference
β-dystroglycan	binds to Class I	Y892	ND	–	16
ErbB-4	binds to Class I	Y1056	ligand-dependent autophosphorylation	–	29
FE65	Class II	Y547	c-Abl	No	36
Itch	Class I	Y371	Fyn	No	49
c-Jun	binds to Class I	Y170	c-Abl	–	50
Magi1	Class I	Y373, Y858	c-Src phosphatase:PTPrz	Yes, No	17
Nedd4.1	Class I	Y43, Y585	c-Src	No	42
Nedd4.2	Class I, IV	Y71, Y457	c-Abl	No	40
Taz (WWTR1)	Class I	Y316	c-Abl	No	34
Wwox	Class I	Y287	Ack	No	51
		Y33	c-Src	Yes	8
Yap	Class I	Y357	c-Src/c-Yes	No	19,32
			c-Abl		31

Note: This table summarizes the tyrosine phosphorylated proteins described in the text whose phosphorylation sites and/or kinases have been specifically characterized.