Figure 4.

Homology between orthologs WWOX protein sequences. Alignment of WWOX protein sequences from human, chicken, Drosophila melanogaster, zebrafish, and mouse. Majority sequence is indicated with color coding for identity between 6, 5, 4, 3, and 2 sequences. The two WW domains are indicated by blue shading. Sequences comprising the SDR enzyme are indicated by red shading, and the putative “WWOX substrate binding site” is shaded in green. (A color version of this figure is available in the online journal.)