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Pretreatment with polydatin prevents Ang II-induced NADPH oxidase activity in rats. (a) NADPH oxidase activity was measured in heart of rats treated with control vehicle, Ang II infusion, polydatin, or Ang II infusion plus polydatin. (b–d) The protein expression of NOX2, NOX4, and NOX1 were detected by Western blotting. Results were expressed as means ± SE (n = 6). *P < 0.05 versus control values. #P < 0.05 versus Ang II alone
