Table 1.
Changes in cardiac function (mean ± SD)
| Group | n | LVEF (%) | LVFS (%) | CO (L/min) | LVEDd (mm) |
|---|---|---|---|---|---|
| Sham | 5 | 68.39 ± 2.44 | 41.17 ± 5.81 | 3.86 ± 0.73 | 3.51 ± 0.34 |
| CME | 5 | 51.03 ± 3.41a | 27.17 ± 7.84a | 2.92 ± 0.83a | 4.96 ± 0.58a |
| CME + siRNA-PDCD4 | 5 | 65.47 ± 2.71b | 41.92 ± 5.63b | 3.85 ± 0.89b | 3.72 ± 0.34b |
| CME + siRNA-control | 5 | 49.71 ± 3.75a | 26.14 ± 8.07a | 2.86 ± 0.77a | 5.11 ± 0.68a |
LVEF: left ventricle ejection fraction; CO: cardiac output; LVEDd: left ventricular end-diastolic diameter; LVFS: left ventricle fractional shortening.
a
P < 0.05, compared with the sham group.
b
P < 0.05, compared with CME group.