Figure 2.

Effect of BV administration on the serum DHT production and mRNA level of 5α-reductase 2 in prostate tissues of BPH-induced rat models. (a) Serum concentrations of DHT were determined using ELISA assay. (b) Expression of mRNA for 5α-reductase 2 in prostate tissue was analyzed by quantitative real-time PCR. Con (control group); BPH (BPH-induced group); Fina (BPH-induced group treated with finasteride 5 mg/kg/day; p.o.); BV (BPH-induced group treated with BV 0.1 mg/kg/day; i.p.). The data shown represent mean ± SEM of six rats per group. ^#p < 0.05 vs. Con group; **p < 0.01, ***p < 0.001 vs. BPH group